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Strain Name: B6;129-Egftm1Dle Tgfatm1Unc
MMRRC ID #: 11535 Date : July 21, 2011 Reference 1 (blue) : C57BL/6J Reference 2 (red) : 129P2/OlaHsd Gene location: Chr3 129,380,493 bp - 129,458,240 bp Size of interval containing gene (includes ambiguous regions): 30.07 Mb (129.93 Mb - 160.00 Mb) Gene location: Chr6 86,145,420 bp - 86,225,151 bp Size of interval containing gene (includes ambiguous regions): 44.95 Mb ( 49.18 Mb - 94.14 Mb) Notes for B6;129-Egftm1Dle Tgfatm1Unc: Genotyping for MMRRC#11535 was performed on ONE homozygous male mouse that was 5 generations intercrossed within the strain relative to the original mice submitted to the MMRRC-UNC archive by the donating investigator. When compared to C57BL/6J (Reference 1) and 129P2/E14 (Reference 2) genotypes, MUGA genotyping indicated that the strain background was very heterogeneous: 44.04% C57BL/6J, 23.16% 129P2/OlaHsd, and 30.43% heterozyous. Two 129P2/OlaHsd homozygous intervals were identified on Chromosome 3 (spanning the Egf locus) and on Chromosome 6 (spanning the Tgfa locus). There is a small portion of the genome that is unknown (1.85%) that is likely due to prior breeding with HbEgf-/-mice. The strain background for this sample is consistent with the information provided by the donating investigator on the strain detail sheet.
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